As if being a Type 2 diabetic isn’t difficult enough, now you have to question each and very new medication that comes to market. The latest wave of new medications to treat Type 2 Diabetes are medicines contacting saxagliptin and alogliptin. These drugs are commonly marketed as Onglyza and Kombiglyze XR.
According to two clinical trials, more patients who received Onglyza and Kombiglyze (as well as other medications containing saxagliptin or alogliptin) suffered heart failure compared to patients in the clinical trials taking placebos. As many were 39 out of every 1,000 patients suffered heart failure. An unacceptable amount to be considered safe, even for the FDA.
As a result of these clinical trials and ongoing reports of adverse cardiovascular effects, the FDA required a new warning be added to the medications informing patients and doctors of the potential risk of heart failure. These warnings were strongly recommended by the endocrinologist/panelists reviewing the data from the clinical trials.
“Incretins” Such as Onglyza Have Been Controversial Since Their Introduction
Onglyza belongs to a new class of medications known as incretins. Januvia was the first drug of this new class of drugs. These drugs have been a source of controversy since they were introduced due to the potentially dangerous side effects associated with their use.
Onglyza Was Marketed Before Adequate Testing Was Done to Determine Health Risks
Astra Zeneca and Bristol-Myers Squibb began marketing Onglyza in 2009 before it conducted adequate clinical trials to see if the new drug posed cardiac risks such as heart attacks, congestive heart failure, and death. This marketing plan ignored the FDA’s recommendations that new drugs be thoroughly investigated and vetted to prove they don’t have an unacceptable risk of injury to patients.
This sequence of events is all too typical in today’s age of Big Pharma. Medications are rushed to market as soon as possible and often ahead of meaningful, insightful ongoing clinical trials that can shed light on the potential dangers associated with these new medicines. Diabetics have been marketed many new medications in recent years due to scientific breakthroughs. Many of these new medicines, such as Onglyza and Kombiglyze, come with a very high risk of cardiovascular-related injuries. Often times the drug companies fail to adequately warn of these dangers.
Although the new warnings are a good start, for many diabetics that have been taking Onglyza and Kombiglyze XR, they are too late. Currently, over 100 lawsuits have been filed against the manufacturers of these medications due to heart-related injuries.
Complications from Taking Onglyza Include Heart Failure, Pancreatitis, and More
In addition to the cardiovascular injuries associated with these diabetic drugs, there are also reports of pancreatitis and pancreatic cancer being associated with Onglyza and Kombiglyze. Unfortunately, it doesn’t stop there. New reports are surfacing that may link a dangerous muscle deterioration condition know as rhabdomyolysis. As time goes by more and more injuries may be linked.
The lack of warnings from these medications have also affected the endocrinologist and other doctors that prescribed these new drugs to their patients based upon the drug company’s representation that they were safe. Many times they rely on what the drug companies tell them concerning the safety of their medicines and unknowingly prescribe dangerous drugs to their patients.
Serious Side Effects Associated with Onglyza and Other Similar Diabetic Medications Include:
- Heart failure
- Pancreatic cancer
- Hemorrhagic pancreatitis
- Necrotizing pancreatitis
- Kidney failure
- Thyroid cancer
Our Kentucky Drug Injury Attorneys Are Here to Help
Gray & White has represented patients against drug companies for defective and unsafe products for over twenty-five years. We have a solid history of success in Kentucky and throughout the nation handling these types of lawsuits. Our offices are located in Kentucky but we handle cases throughout the country. If you or a loved one believe you were harmed by Onglyza, Kombiglyze XR or another diabetes medication, contact us for a FREE CONSULTATION.